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Dopamine agonists DA prevent tumor growth, but usually suppress prolactin PRL both in mother and fetus.
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Possible long-term consequences on fetal development remain unknown. Other 26 pregnancies in 21 patients were incompletely evaluated and included only in the pregnancy outcome and cure rate analysis.
Treated patients were compared with the control group Y 8 women with PRM who discontinued DA after pregnancy induction 9 pregnancies and a control group Z of 46 healthy pregnant women, randomly selected from two departments of Obstetrics. Patients with multiple pregnancies were recorded in each corresponding study group.
Two patients with PRM-induced neuroophthalmic syndrome were successfully treated with DA throughout 1 and respectively 3 pregnancies. Maintaining physiological serum PRL levels during pregnancy frequently with low doses of DA prevented tumor growth, avoiding a PRL suppression that may have subtle influence on long-term foetal development.
Radiological evidence for regression of prolactinoma after treatment with bromocriptine.
Lancet ; 2 Effects of bromocriptine on pituitary tumour size. Br Med J ; 2 Treatment of prolactinomas. Ann Med ; 30 5 Bromocriptine treatment of pituitary adenomas. Evaluation of withdrawal effect.
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Pregnancy outcome after treatment with the ergot derivative, cabergoline. Reprod Toxicol ; 10 4 Pregnancy outcome after cabergoline treatment in early weeks of gestation. Reprod Toxicol ; 16 6 Pregnancy induced and maintained under 2-Br-alfa-ergocryptin in a patient with evolutive prolactinoma in Romanian. Obstetrica si Ginecologia ; Drugs in pregnancy and lactation.
Dynamics of human chorionic gonadotropin, prolactin, and growth hormone in serum and amniotic fluid throughout normal human pregnancy.
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Am J Obstet Gynecol ; 7 long term effects of prostate removal 2017 Ben Jonathan N, Hnasko R. Dopamine as a prolactin PRL inhibitor. Endocr Rev ; 22 6 A pregnancy in an acromegalic woman during bromocriptine treatment: effects on growth hormone and prolactin in the maternal, fetal, and amniotic compartments.
Handwerger S, Freemark M. Role of placental lactogen and prolactin in human pregnancy.
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Adv Exp Med Biol ; Early pregnancy loss. Size and shape of the pituitary gland during pregnancy and post partum: measurement with MR imaging.
Radiology ; 2 Pituitary gland control prostate enlargement during normal pregnancy: an in vivo study using magnetic resonance imaging.
Am J Med ; 85 2 The pituitary gland in pregnancy: a clinicopathologic and immunohistochemical study of 69 cases.
Mayo Clin Proc ; 65 4 Visual loss in pregnant women with pituitary adenomas. Ann Intern Med ; 7 Molitch ME. Pregnancy and the hyperprolactinemic woman. Visual field defects and reduced visual acuity during pregnancy in two patients with prolactinoma: rapid regression of symptoms under bromocriptine. Case reports.
Br J Obstet Gynaecol ; 91 8 Continuous administration of bromocriptine in the prevention of neurological complications in pregnant women with prolactinomas. Am J Obstet Gynecol ; 8 Tumor size changes in prolactinomas treated with minimum bromocriptine throughout gestation.
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Gynecological Endocrinology ; 14 suppl 2 Bromocriptine as prophylactic therapy in prolactinoma during pregnancy. Fertil Steril ; 36 4